刘泳研究组
刘泳 教授
发布时间:2020年11月16日
浏览次数:

刘泳,博士,教授,博士生导师。本科、硕士毕业于中国海洋大学,2010年博士毕业于中国科学院动物研究所膜生物学国家重点实验室。2011年至2016年在美国University of North Carolina at Chapel Hill作为博士后研究p53的代谢调控功能。2017年入选江苏省特聘教授,加入徐州医科大学肿瘤生物治疗国家地方联合工程实验室,建立肿瘤代谢研究组。从糖脂代谢角度出发,研究小分子代谢物对于肿瘤关键信号分子的修饰及功能影响,先后在包括PNAS、EMBO Journal、Clinincal Cancer Research、Cell Death & Differentiation、Trends in Cancer等刊物发表论文二十余篇,授权专利2项。作为项目主持人获得国家自然科学基金、江苏省重点研发计划、江苏省高校重大研究项目资助。刘泳博士是中国细胞生物学会细胞代谢专业委员会委员,中国抗癌协会肿瘤标志物专业委员会委员,中国医师协会细胞代谢与治疗专业委员会委员。

代表论文:

Nianli Liu,Zhiyuan Wu,Aoxing Chen,Yuqi Wang,Dafei Cai,Junian Zheng,Yong Liu& Longzhen Zhang. SNRPB promotes the tumorigenic potential of NSCLC in part by regulating RAB26. (2019)Cell Death & Disease(Co-corresponding author)

Liu, Yong, Leslie, Patrick, Jin, Aiwen, Itahana, Koji, Graves, Lee, and Zhang, Yanping. p32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression.FASEB journal. 2018 Feb 20:fj201701004RR. doi: 10.1096/fj.201701004RR.

Liu, Yong, Leslie, Patrick, Jin, Aiwen, Itahana, Koji, Graves, Lee, and Zhang, Yanping. p32 heterozygosity protects against age- and diet-induced obesity by increasing energy expenditure.Scientific reports. 2017. 7(1), 5754.

Liu, Yong, Chad Deisenroth, and Yanping Zhang. RP-MDM2-p53 pathway: linking ribosomal biogenesis and tumor surveillance.Trends in Cancer. April, 2016. 2(4), 191–204.

Liu, Yongand Yanping Zhang. CHCHD2 connects mitochondrial metabolism to apoptosis.Molecular & Cellular Oncology. 2015 vol 2(4), doi: 10.1080/23723556.2015.1004964

Liu, Yong, Hilary V. Clegg, Jiehui Di, Laura A. Tollini, Yizhou He, Aiwen Jin, and Yanping Zhang. CHCHD2 inhibits apoptosis through interaction with Bcl-xL to regulate Bax activation.Cell Death & Differentiation. 2015 Jun;22(6):1035-46. doi: 10.1038/cdd.2014.194.

Liu, Yong, Yizhou He, Aiwen Jin, Andrey P. Tikunov, Lishi Zhou, Laura A. Tollini, Patrick Leslie, Lei O. Li, Rosalind A. Coleman, Zhennan Gu, Yong Q. Chen, Jeffrey M. Macdonald, Lee M. Graves, and Yanping Zhang. The RP-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation. 2014.Proceedings of the National Academy of Sciences.2014 June 10. vol. 111 no. 23 E2414-E2422.

Liu, Yong, Cheng He, Zhou Yuchang, Zhu Yushan, Bian Rui, Chen Yuewen, Li Changyin, Ma Qi, Zheng Qiaoxia, Zhang Yong, Jin Haijing, Wang Xiaohui, Chen Quan, Zhu Dahai. Myostatin induces mitochondrial metabolic alteration and typical apoptosis in cancer cells.Cell Death & Disease. 2013. 4: e494; doi: 10.1038/ccdis.2013.31

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