研究成果
发布时间:2024年04月13日
浏览次数:

代表性研究成果(按发表年份排序):

1.Bispecific CAR T-cell therapy targeting BCMA and CD19in relapsed/refractory multiple myeloma: a phase l/l trial.Nature communications. 2024 Apr 12.(IF =16.6)

2.In vivo manufacture and manipulation of CAR‑T cells for better druggability. Cancer and Metastasis Reviews. 2024 Apr 9. doi: 10.1007/s10555-024-10185-8.(IF = 9.2)

3.Armed with IL-2 based fusion protein improves CAR-T cell fitness and efficacy against solid tumors. BBA-Molecular Basis of Disease. 2024 Apr 5:167159. doi: 10.1016/j.bbadis.2024.167159.(IF = 6.2)

4.Bispecific BCMA/CD19 targeted CAR‑T cell therapy forces sustained disappearance ofsymptoms andanti‑acetylcholine receptor antibodies inrefractory myasthenia gravis: acase report.Journal of Neurology,2024 Apr11,doi.org/10.1007/s00415-024-12367-4(IF = 6.0)

5.AURKA inhibitor-induced PD-L1 upregulation impairs antitumor immune responses. Front Immnunol. 2023 Sep 12:14:1182601. doi: 10.3389/fimmu.2023.1182601.(IF =7.3)

6.Long-Term Follow-Up of Combination of B-Cell Maturation Antigen and CD19 Chimeric Antigen Receptor T Cells in Multiple Myeloma. J Clin Oncol. 2022 Jul 10;40(20):2246-2256.(IF = 45.3)

7.Safety and efficacy of a humanized CD19 chimeric antigen receptor T Cells for relapsed/refractory acute lymphoblastic leukaemia. Am J Hematol. 2022 Jun 1;97(6):711-718.(IF = 12.8)

8.Efficacy and safety of CD19-specific CAR T cell-based therapy in B-cell acute lymphoblastic leukemia patients with CNSL. Blood. 2022 Jun 9;139(23):3376-3386.(IF = 20.3)

9.An immune-related gene prognostic risk index for pancreatic adenocarcinoma. Front Immnunol.2022,13:945878.(IF = 7.3)

10.Blockade of AIM2 inflammasome or α1-AR ameliorates IL-1β release and macrophage-mediated. J Immunother Cancer. 2021, 9(1):e001466.(IF = 10.9)

11.CRISPR screen in mechanism and target discovery for cancer immunotherapy. Biochim Biophys Acta Rev Cancer. 2020, 1874(1):188378.(IF = 11.2)

12.β2-AR activation promotes cleavage and nuclear translocation of Her2 and metastatic potential of cancer cells. Cancer Sci.2020,111(12):4417-4428.(IF = 5.7)

13.A combination of humanised anti-CD19 and anti-BCMA CAR T cells in patients with relapsed or refractory multiple myeloma: a single-arm, phase 2 trial. Lancet Haematol. 2019 Oct;6(10):e521-e529.(IF = 24.7)

14.Neural regulation of drug resistance in cancer treatment. Biochim Biophys Acta Rev Cancer. 2019 Jan;1871(1):20-28.(IF =11.2)

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