孙楠，博士，讲师。硕博毕业于中国农业科学院哈尔滨兽医研究所，在陈化兰院士团队从事流感病毒致病机制和宿主抗病毒天然免疫研究。目前主要研究方向为新型溶瘤腺病毒的开发应用和机制探索；主持国家自然科学基金青年项目1项、江苏省高校面上项目1项、徐州医科大学优秀人才科学启动基金1项、指导大学生获得创新创业训练计划项目2项；申请国家发明专利5项，其中获得国家授权专利2项；先后在Protein & Cell、PLoS Pathogens、mBio、Journal of Virology、Inflammation等杂志发表文章。
代表作文章：
1.Sun N*,Jiang L, Ye M M, Wang Y H, Wang G W, Wan X P, Zhao Y H, Wen X, Li Q B, Ma S J, Liu L L, Bu Z G, Chen H L, Li C, 2020. TRIM35 mediates protection against influenza infection by activating TRAF3 and degrading viral PB2.Protein & Cell. 2020, 1112(12):894-914.
2.Sun N*, Zhang J, Zhang C, Xie T, Zhang Z, Wang X, Li W, Zhang Y, Chen Z, Zheng J, Fang L, Wang G. Inhibition of human adenovirus replication by TRIM35-mediated degradation of E1A.J Virol. 2023. 97(8): p. e0070023.
3. Zhang J, Wu Y, Wang Y, Wang J, Ye Y, Yin H, Sun N, Qin B,Sun N*. TRIM35 Negatively Regulates the cGAS-STING-Mediated Signaling Pathway by Attenuating K63-Linked Ubiquitination of STING.Inflammation. 2024.
4. Jikai Zhang, Botao Zou, Yunfeng Geng, Hang Yin, Baoying Qin, Wanjun Gao, Xiaoman Lin,Nan Sun*. TRIM36 serves as a prognostic indicator linked to immune infiltration in KIRC.Heliyon. 2025 Feb 28;11(4): e42540.
5. Liang L, Jiang L, Li J, Zhao Q, Wang J, He X, Huang S, Wang Q, Zhao Y, Wang G,Sun N, Deng G, Shi J, Tian G, Zeng X, Jiang Y, Liu L, Liu J, Chen P, Bu Z, Kawaoka Y, Chen H And Li C, 2019. Low Polymerase Activity Attributed to PA Drives the Acquisition of the PB2 E627K Mutation of H7N9 Avian Influenza Virus in Mammals.mBio. 2019 Jun 18;10(3). pii: e01162-19.
6. Luo W, Zhang J, Liang L, Wang G, Li Q, Zhu P, Zhou Y, Li J, Zhao Y,Sun N, Huang S, Zhou C, Chang Y, Cui P, Chen P, Jiang Y, Deng G, Bu Z, Li C, Jiang L And Chen H, 2018. Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication.PLoS Pathog. 2018 Jan 19;14(1): e1006851.
7. Wang G, Jiang L, Wang J, Zhang J, Kong F, Li Q, Yan Y, Huang S, Zhao Y, Liang L, Li J,Sun N, Hu Y, Shi W, Deng G, Chen P, Liu L, Zeng X, Tian G, Bu Z, Chen H And Li C, 2020. The G Protein-Coupled Receptor FFAR2 Promotes Internalization during Influenza A Virus Entry.J Virol. 2020 Jan; 94(2): e01707-19.
8. Zhu P, Liang L, Shao X, Luo W, Jiang S, Zhao Q,Sun N, Zhao Y, Li J, Wang J, Zhou Y, Zhang J, Wang G, Jiang L, Chen H And Li C, 2017. Host Cellular Protein TRAPPC6ADelta Interacts with Influenza A Virus M2 Protein and Regulates Viral Propagation by Modulating M2 Trafficking.J Virol. 2017 Jan 1; 91(1): e01757-16.
