免疫增效纳米材料子方向负责人
gegao@xzhmu.edu.cn
高歌，博士，1995年生，徐州医科大学肿瘤生物治疗研究所副教授，“百人计划”导师，硕士生导师。2016年6月，本科毕业于东南大学生物科学与医学工程学院，获得学士学位。硕博毕业于东南大学生物科学与医学工程学院，期间在生物电子学国家重点实验室从事多肽前药/纳米材料在癌症诊疗方面的研究。于2022年6月获东南大学博士学位，硕士导师为青年拔尖人才获得者吴富根教授，博士导师为国家杰出青年基金获得者梁高林教授。
2022年7月进入徐州医科大学江苏省肿瘤生物治疗研究所工作。目前从事多肽水凝胶、纳米材料在细胞治疗方面的研究，至今，在Advanced Materials、Journal of the American Chemical Society、Advance Functional Materials、Biomaterials、Nano Letters等国际知名期刊共发表论文36篇。其中，以第一作者/通讯作者身份发表SCI论文14篇，一区9篇，二区6篇，IF>10分11篇，累计IF>220。2篇入选ESI“世界前1%高被引论文”。在研项目主要包括：国家自然科学基金1项（批准号：22305208），江苏省自然科学基金1项（批准号：BK20230680），江苏省高校自然科学基金项目重大项目1项（批准号：24KJA320010），2024年江苏省青年科技人才托举工程，2024年度徐州医科大学青年科技创新团队培育计划，2024年度徐州医科大学科技人才“高峰计划”，以及徐州医科大学优秀人才科研启动基金。邮箱：gegao@xzhmu.edu.cn。
代表论文：
1.Ge Gao#,*, Yao-Wen Jiang#, Jiaxuan Chen, Xiaodi Xu, Xianbao Sun, Haidong Xu, Gaolin Liang, Xiaoyang Liu, Wenjun Zhan, Meng Wang, Yixin Xu, Junnian Zheng*, Gang Wang*. Three-in-One Peptide Prodrug with Targeting, Assembly and Release Properties for Overcoming Bacterium-Induced Drug Resistance and Potentiating Anti-Cancer Immune Response.Adv. Mater.2024, 2312153 (中科院一区，影响因子27.4)
2. Jiaxuan Chen, Xiaodi Xu, Kexuan Wang, Mingxia Xue, Qing Wang, Weixiang Zhong, Yan Wan, Xiaoyang Liu, Junnian Zheng,Ge Gao*, Gang Wang*. Hypoxia-activated liposomes enable synergistic photodynamic therapy for oral cancer.Adv. Healthcare Mater.2025, 2404395. (中科院二区，影响因子10.0)
3.Ge Gao#, Yao-Wen Jiang#, Wenjun Zhan, Xiaoyang Liu, Runqun Tang, Xianbao Sun, Yu, Deng, Lingling Xu, Gaolin Liang*. Trident Molecule with Nanobrush–Nanoparticle–Nanofiber Transition Property Spatially Suppresses Tumor Metastasis.J. Am. Chem. Soc.2022,144, 11897−11910.(中科院一区，影响因子14.357)
4.Ge Gao#, Xianbao Sun#, Xiaoyang Liu, Runqun Tang, Manli Wang, Wenjun Zhan, Junnian Zheng,* Gaolin Liang*. FAP-α-Instructed Coumarin Excimer Formation for High Contrast Fluorescence Imaging of Tumor.Nano Lett.2022,22, 6782−6786.(中科院一区，影响因子12.262)
5.Ge Gao#, Xianbao Sun#, Xiaoyang Liu, Yao-Wen Jiang, Runqun Tang, Yuxin Guo, Fu-Gen Wu,* Gaolin Liang*. Intracellular Nanoparticle Formation and Hydroxychloroquine Release for Autophagy-Inhibited Mild-Temperature Photothermal Therapy for Tumors.Adv. Funct. Mater.2021,31, 2102832.(中科院一区，SCI，影响因子19.925)
6.Ge Gao, Xianbao Sun*, Gaolin Liang*. Nanoagent-Promoted Mild-Temperature Photothermal Therapy for Cancer Treatment.Adv. Funct. Mater.2021,31, 2100738.(中科院一区，影响因子19.925)
7.Ge Gao, Yao-Wen Jiang, Yuxin Guo, Hao-Ran Jia, Xiaotong Cheng, Yu Deng, Xin-Wang Yu, Ya-Xuan Zhu, Hao-Yue Guo, Wei Sun, Xiaoyang Liu, Jing Zhao, Shihe Yang, Zhi-Wu Yu, Fatima Maria Sierrs Raya, Gaolin Liang*, Fu-Gen Wu*. Enzyme‐Mediated Tumor Starvation and Phototherapy Enhance Mild‐Temperature Photothermal Therapy.Adv. Funct. Mater.2020,30, 1909391.(中科院一区，影响因子19.925，ESI高被引论文)
8.Ge Gao, Yao-Wen Jiang, Wei Sun, Yuxin Guo, Hao-Ran Jia, Xin-Wang Yu, Guang-Yu Pan, Fu-Gen Wu*. Molecular Targeting‐Mediated Mild‐Temperature Photothermal Therapy with a Smart Albumin‐Based Nanodrug.Small2019,15, 1900501.(中科院二区，影响因子15.153)
9.Ge Gao#, Yao-Wen Jiang#, Hao-Ran Jia, Wei Sun, Yuxin Guo, Xin-Wang Yu, Xiaoyang Liu, Fu-Gen Wu*. From perinuclear to intranuclear localization: A cell-penetrating peptide modification strategy to modulate cancer cell migration under mild laser irradiation and improve photothermal therapeutic performance.Biomaterials2019,223, 119443.(中科院一区，影响因子15.304)
10.Ge Gao#,Yao-Wen Jiang#, Hao-Ran Jia, Fu-Gen Wu*. Near-infrared light-controllable on-demand antibiotics release using thermo-sensitive hydrogel-based drug reservoir for combating bacterial infection.Biomaterials2019,188, 83−95.(中科院一区，影响因子15.304，ESI高被引论文)
11.Ge Gao#, Yao-Wen Jiang#, Hao-Ran Jia, Jingjing Yang, Fu-Gen Wu*. On-off-on fluorescent nanosensor for Fe3+detection and cancer/normal cell differentiation via silicon-doped carbon quantum dots.Carbon2018,134, 232−243.(中科院一区，影响因子11.307)
12.Ge Gao, Yao-Wen Jiang, Jingjing Yang, Fu-Gen Wu*. Mitochondria-targetable carbon quantum dots for differentiating cancerous cells from normal cells.Nanoscale2017,9, 18368−18378.(中科院二区，影响因子8.307)
13.Ge Gao, Yao-Wen Jiang, Wei Sun, Fu-Gen Wu*. Fluorescent quantum dots for microbial imaging.Chin. Chem. Lett.2018,29, 1475−1485.(中科院二区，影响因子8.455)
14.XiangShi#,Ge Gao#,Xiaoyang Liu,Lingling Xu, Yu Deng, Rui Wang*, Gaolin Liang*. Highly lipophilic coumarin fluorophore with excimer-monomer transition property for lipid droplet imaging.Chin. Chem. Lett.2023,34,107613.(共同一作，中科院二区，影响因子8.455)
15.Yao-Wen Jiang#,Ge Gao#, Pengcheng Hu#, Jia-Bao Liu, Yuxin Guo, Xiaodong Zhang, Xin-Wang Yu, Fu-Gen Wu*, Xiaolin Lu*. Palladium nanosheet-knotted injectable hydrogels formed via palladium–sulfur bonding for synergistic chemo-photothermal therapy.Nanoscale2020,12, 210−219.(共同一作，中科院二区，影响因子8.307)
16.Jingjing Yang#,Ge Gao#, Xiaodong Zhang, Yong-Hao Ma, Hao-Ran Jia, Yao-Wen Jiang, Zhifei Wang*, Fu-Gen Wu*. Ultrasmall and photostable nanotheranostic agents based on carbon quantum dots passivated with polyamine-containing organosilane molecules.Nanoscale2017,9, 15441−15452.(共同一作，中科院二区，影响因子8.307)
