免疫增效纳米材料子方向负责人
gegao@xzhmu.edu.cn
高歌,博士,1995年生,徐州医科大学肿瘤生物治疗研究所副教授,“百人计划”导师,硕士生导师。2016年6月,本科毕业于东南大学生物科学与医学工程学院,获得学士学位。硕博毕业于东南大学生物科学与医学工程学院,期间在生物电子学国家重点实验室从事多肽前药/纳米材料在癌症诊疗方面的研究。于2022年6月获东南大学博士学位,硕士导师为青年拔尖人才获得者吴富根教授,博士导师为国家杰出青年基金获得者梁高林教授。
2022年7月进入徐州医科大学江苏省肿瘤生物治疗研究所工作。目前从事多肽水凝胶、纳米材料在细胞治疗方面的研究,至今,在Journal of the American Chemical Society、Nano Letters、Advance Functional Materials等国际知名期刊共发表论文34篇。其中,以第一作者发表SCI论文14篇,一区9篇,二区5篇,IF>10分9篇,累计IF>185。3篇入选ESI“世界前1%高被引论文”。在研项目主要包括:国家自然科学基金1项(批准号:22305208),江苏省自然科学基金1项,徐州医科大学优秀人才科研启动基金(2023.01-2027.12,批准号:RC20552215)。邮箱:gegao@xzhmu.edu.cn。
代表论文:
1.Ge Gao#, Yao-Wen Jiang#, Wenjun Zhan, Xiaoyang Liu, Runqun Tang, Xianbao Sun, Yu, Deng, Lingling Xu, Gaolin Liang*. Trident Molecule with Nanobrush–Nanoparticle–Nanofiber Transition Property Spatially Suppresses Tumor Metastasis.J. Am. Chem. Soc.2022, 144, 11897−11910.(中科院一区,影响因子14.357)
2.Ge Gao#, Xianbao Sun#, Xiaoyang Liu, Runqun Tang, Manli Wang, Wenjun Zhan, Junnian Zheng,* Gaolin Liang*. FAP-α-Instructed Coumarin Excimer Formation for High Contrast Fluorescence Imaging of Tumor.Nano Lett.2022, 22, 6782−6786.(中科院一区,影响因子12.262)
3.Ge Gao#, Xianbao Sun#, Xiaoyang Liu, Yao-Wen Jiang, Runqun Tang, Yuxin Guo, Fu-Gen Wu,* Gaolin Liang*. Intracellular Nanoparticle Formation and Hydroxychloroquine Release for Autophagy-Inhibited Mild-Temperature Photothermal Therapy for Tumors.Adv. Funct. Mater.2021, 31, 2102832.(中科院一区,SCI,影响因子19.925)
4.Ge Gao, Xianbao Sun*, Gaolin Liang*. Nanoagent-Promoted Mild-Temperature Photothermal Therapy for Cancer Treatment.Adv. Funct. Mater.2021, 31, 2100738.(中科院一区,影响因子19.925)
5.Ge Gao, Yao-Wen Jiang, Yuxin Guo, Hao-Ran Jia, Xiaotong Cheng, Yu Deng, Xin-Wang Yu, Ya-Xuan Zhu, Hao-Yue Guo, Wei Sun, Xiaoyang Liu, Jing Zhao, Shihe Yang, Zhi-Wu Yu, Fatima Maria Sierrs Raya, Gaolin Liang*, Fu-Gen Wu*. Enzyme‐Mediated Tumor Starvation and Phototherapy Enhance Mild‐Temperature Photothermal Therapy.Adv. Funct. Mater.2020, 30, 1909391.(中科院一区,影响因子19.925,ESI高被引论文)
6.Ge Gao, Yao-Wen Jiang, Wei Sun, Yuxin Guo, Hao-Ran Jia, Xin-Wang Yu, Guang-Yu Pan, Fu-Gen Wu*. Molecular Targeting‐Mediated Mild‐Temperature Photothermal Therapy with a Smart Albumin‐Based Nanodrug.Small2019, 15, 1900501.(中科院一区,影响因子15.153)
7.Ge Gao#, Yao-Wen Jiang#, Hao-Ran Jia, Wei Sun, Yuxin Guo, Xin-Wang Yu, Xiaoyang Liu, Fu-Gen Wu*. From perinuclear to intranuclear localization: A cell-penetrating peptide modification strategy to modulate cancer cell migration under mild laser irradiation and improve photothermal therapeutic performance.Biomaterials2019, 223, 119443.(中科院一区,影响因子15.304)
8.Ge Gao#, Yao-Wen Jiang#, Hao-Ran Jia, Fu-Gen Wu*. Near-infrared light-controllable on-demand antibiotics release using thermo-sensitive hydrogel-based drug reservoir for combating bacterial infection.Biomaterials2019, 188, 83−95.(中科院一区,影响因子15.304,ESI高被引论文)
9.Ge Gao#, Yao-Wen Jiang#, Hao-Ran Jia, Jingjing Yang, Fu-Gen Wu*. On-off-on fluorescent nanosensor for Fe3+detection and cancer/normal cell differentiation via silicon-doped carbon quantum dots.Carbon2018, 134, 232−243.(中科院一区,影响因子11.307,ESI高被引论文)
10.Ge Gao, Yao-Wen Jiang, Jingjing Yang, Fu-Gen Wu*. Mitochondria-targetable carbon quantum dots for differentiating cancerous cells from normal cells.Nanoscale2017, 9, 18368−18378.(中科院二区,影响因子8.307)
11.Ge Gao, Yao-Wen Jiang, Wei Sun, Fu-Gen Wu*. Fluorescent quantum dots for microbial imaging.Chin. Chem. Lett.2018, 29, 1475−1485.(中科院二区,影响因子8.455)
12.XiangShi#,Ge Gao#,Xiaoyang Liu,Lingling Xu, Yu Deng, Rui Wang*, Gaolin Liang*. Highly lipophilic coumarin fluorophore with excimer-monomer transition property for lipid droplet imaging.Chin. Chem. Lett.2023, 34,107613.(共同一作,中科院二区,影响因子8.455)
13.Yao-Wen Jiang#,Ge Gao#, Pengcheng Hu#, Jia-Bao Liu, Yuxin Guo, Xiaodong Zhang, Xin-Wang Yu, Fu-Gen Wu*, Xiaolin Lu*. Palladium nanosheet-knotted injectable hydrogels formed via palladium–sulfur bonding for synergistic chemo-photothermal therapy.Nanoscale2020, 12, 210−219.(共同一作,中科院二区,影响因子8.307)
14.Jingjing Yang#,Ge Gao#, Xiaodong Zhang, Yong-Hao Ma, Hao-Ran Jia, Yao-Wen Jiang, Zhifei Wang*, Fu-Gen Wu*. Ultrasmall and photostable nanotheranostic agents based on carbon quantum dots passivated with polyamine-containing organosilane molecules.Nanoscale2017, 9, 15441−15452.(共同一作,中科院二区,影响因子8.307)